136 research outputs found

    Prediction of mechanical and electrical properties of carbon fibre-reinforced self-sensing cementitious composites

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    The transmission of signal values in self-sensing concrete allows us to precisely locate damaged structures and prevent disasters. Currently, there are over ten functional materials used in self-sensing concrete applications. Carbon fibre (CF) is a well-known functional material that has been extensively studied for its reproducibility and accuracy in self-sensing concrete experiments. In contrast, this study is based on finite element modelling to rapidly predict the impact of the functional filler material, CF, on concrete performance. This paper simulates the mechanical and piezoresistive properties of concrete with unsized and desized short-cut CFs at lengths of 3, 6, and 12 mm. Four different weight ratios were considered for each type of CF. The results indicate that the inclusion of CF increases compressive strength by approximately 2 MPa, while flexural strength can increase by up to 39%, with the unsized 6 mm fibres performing best at a concentration of 0.7 wt%. In the piezoresistive model, the higher fractional change in resistivity between 0 and 2 MPa is attributed to the formation of a conductive circuit. The predicted trends in mechanical strength and resistance variation align well with experimental observations. Therefore, this proposed model holds the potential to aid in the development of design strategies aimed at fine-tuning the microstructure of these self-sensitive materials to enhance performance and facilitate the design and application of carbon fibres in cementitious composites

    Behavior and Modeling of Circular Large Rupture Strain FRP-Confined Ice under Axial Compression

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    The application of concrete is severely limited in construction in cold areas. However, the local ice has functioned as a potential substitute for concrete for a long time. In order to make efficient use of ice to overcome its weaknesses of low strength and poor ductility, an innovative type of ice-filled large rupture strain (LRS) fiber-reinforced polymer (FRP) tube column was developed. The system consists of external LRS FRP tubes filled with plain ice or sawdust-reinforced ice. This paper presents an experimental investigation into the axial compressive behavior of such composite stub columns with circular sections. The test results confirmed that the axial compressive behavior of the ice cores was greatly improved because of the LRS FRP confinement, as well as the addition of sawdust in ice. The axial stress–strain curves of the LRS FRP-confined ice exhibited monotonically ascending bilinear shapes. Both the compressive strength and the ultimate axial strain of the confined ice were significantly enhanced with an increase of the thickness of the LRS FRP tube. A theoretical model for the LRS FRP-confined ice is proposed, in which the dilation properties (i.e., lateral strain–axial strain relation), as well as the entire axial stress–strain responses of the inner ice cores, are explicitly modeled with reasonable accuracy

    Effect of Preparation Technologies on Properties of Reactive Powder Concrete with Nano-zirconia

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    Reactive powder concrete filled with 3% content of nano-zirconia (NZ) are fabricated to investigate the effect of preparation technologies on the mechanical strength. The preparation technologies involve internal (NZ is added in RPC and replaced cement )/external mixing(NZ is added in RPC but not replaced cement), ultrasonic time, high mixing speed, saturated lime water/high temperature curing media(curing in water at 90℃). The influencing mechanisms of processing method are revealed through X-ray powder diffraction (XRD) and thermogravimetry (TG) analysis, scanning electron microscope observation. Experiment results showed that high mixing speed and high temperature curing media can improve the mechanical strength obviously. The compressive strength of NZ filled reactive powder concrete with high mixing speed increase 49.9%. The compressive strength, flexural strength and splitting strength of reactive powder concrete with NZ under high temperature curing media increase 35%, 15% and 17% respectively compared with control concrete

    Developing Multifunctional Ultra-High Performance Concrete via Incorporating Hybrid Steel Wires and Fibers

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    Stainless steel wires (SSWs) with micro diameter and stainless steel fiber (SFs) with millimeter diameter were incorporated together to develop multifunctional ultra-high performance concrete (UHPC) in this study. The addition of 0.2 vol.% of SSWs can already improve interface between matrix and SFs, reduce the microcracks in UHPC caused by shrinkage and initial load, increase SFs’ distribution and orientation with their high flexibility, thus enhancing the flexural toughness and resulting in the occurrence of multiple cracking flexural failure mode of UHPC with less than 2.0 vol.% SFs. The hybrid SWs and SFs reinforced UHPC possesses low electrical resistivity and can sense its initial cracking, residual flexural loading and cracking development by the measured fractional change in electrical resistivity. This is mainly coming from the inhibition effect of SWs on microcracks and the extensively conductive pathway formed by both SWs and SFs. The multiple cracking failure mode under flexural load and the self-sensing capacity to monitor crack initiation and propagation of UHPC with low content hybrid wires and fibers is important to develop multifunctional UHPC, thus providing a new approach for maintaining sustainable development of infrastructures

    In Vitro Study on Apoptosis Induced by Strontium-89 in Human Breast Carcinoma Cell Line

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    Many radiopharmaceuticals used for medical diagnosis and therapy are beta emitters; however, the mechanism of the cell death caused by beta-irradiation is not well understood. The objective of this study was to investigate the apoptosis of human breast carcinoma MCF-7 cell lines induced by Strontium-89 (89Sr) and its regulation and control mechanism. High-metastatic Breast Carcinoma MCF-7 cells were cultured in vitro using 89Sr with different radioactive concentration. The inhibition rate of cell proliferation was measured by MTT color matching method. The cell cycle retardation, apoptosis conditions, mitochondrion transmembrane potential difference and Fas expression were tested and analyzed. The genes P53 and bcl-2 expressions was also analyzed using immunity histochemical analysis. After being induced by 89Sr with various of radioactive concentration, it was found that the inhibition of cell proliferation of MCF-7 cells was obviously, the retardation of cell cycle occurred mainly in G2-M. It was also found that the obvious apoptosis occurred after being induced by 89Sr, the highest apoptosis rate reached 46.28%. The expressions of Fas acceptor and P53 gene increased, while bcl-2 gene expression decreasesd. These findings demonstrate that in the ranges of a certain radioactive concentration, the inhibition rate of MCF-7 cell proliferation and retardation of cell cycle had positive correlation with the concentration of 89Sr. And the mitochondrion transmembrane potential decrease would induce the apoptosis of MCF-7 cell notably, which were controlled by P53 and bcl-2 genes, involved with the Fas acceptor

    Strain and Damage Self-Sensing of Basalt Fiber Reinforced Polymer Laminates Fabricated with Carbon Nanofibers/Epoxy Composites Under Tension

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    This study investigated the strain and damage self-sensing capabilities of basalt fiber reinforced polymer (BFRP) laminates fabricated with carbon nanofibers (CNFs)/epoxy composites subjected to tensile loadings. The conduction mechanisms based on the tunnel conduction and percolation conduction theories as well as the damage evolution were also explored. A compensation circuit with a half-bridge configuration was proposed. The results indicated the resistivity of the CNFs/BFRP laminates and CNFs/epoxy composites exhibited similar change rule, indicating that the conductive networks of CNFs/BFRP laminates were governed by CNFs/epoxy composites. With the increase of strain under monotonic tensile loading, the electrical resistance response could be classified into three stages corresponding to different damage modes. This confirmed CNFs/BFRP laminates have excellent self-sensing abilities to monitor their internal damages. Moreover, stable and repeatable strain self-sensing capacity of the CNFs/BFRP laminates was verified under cyclic tensile loading because the electrical resistance varied synchronously with the applied strain

    Properties and Mechanisms of Self-Sensing Carbon Nanofibers/Epoxy Composites for Structural Health Monitoring

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    In this paper, carbon nanofibers (CNFs) with high aspect ratio were dispersed into epoxy matrix via mechanical stirring and ultrasonic treatment to fabricate self-sensing CNFs/epoxy composites. The mechanical, electrical and piezoresistive properties of the nanocomposites filled with different contents of CNFs were investigated. Based on the tunneling conduction and percolation conduction theories, the mechanisms of piezoresistive property of the nanocomposites were also explored. The experimental results show that adding CNFs can effectively enhance the compressive strengths and elastic moduli of the composites. The percolation threshold of the CNFs/epoxy composites is 0.186 vol% according to the modified General Effective Media Equation. Moreover, the stable and sensitive piezoresistive response of CNFs/epoxy composites was observed under monotonic and cyclic loadings. It can be demonstrated that adding CNFs into epoxy-based composites provides an innovative means of self-sensing, and the high sensitivity and stable piezoresistivity endow the CNFs/epoxy composites with considerable potentials as efficient compressive strain sensors for structural health monitoring of civil infrastructures

    Calibration of topological development in the procedure of parametric identification: application to the stochastic GreenLab model for Pinus Sylvestris var. Mongolica

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    International audienceArid climate, biophysical conditions and human activities all contribute to the occurrences of ecosystem and environment problems, i.e. water scarcity, desertification, salinization, in arid and semiarid zone of North China. Mongolian Scots pine tree (Pinus sylvestris var. mongolica) is one of the principal species of the windbreak and sand-fixing forest in this area. In this paper, we present the calibration process of stochastic GreenLab model based on experiment data. Specific plant topology and sink–source parameters were estimated for Mongolian Scots pine trees through optimizing procedure. The fitting results showed that the calibration was reasonable and acceptable. The model produces several three-dimensional visual representations of Mongolian Scots pine trees with different topological structures simulated by Monte Carlo methods. This model can be used to describe the plant development and growth in a stand level, taking into accounts the variations in plant topology and biomass

    Association of genetically predicted 486 blood metabolites on the risk of Alzheimer’s disease: a Mendelian randomization study

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    BackgroundStudies have reported that metabolic disturbance exhibits in patients with Alzheimer’s disease (AD). Still, the presence of definitive evidence concerning the genetic effect of metabolites on AD risk remains insufficient. A systematic exploration of the genetic association between blood metabolites and AD would contribute to the identification of new targets for AD screening and prevention.MethodsWe conducted an exploratory two-sample Mendelian randomization (MR) study aiming to preliminarily identify the potential metabolites involved in AD development. A genome-wide association study (GWAS) involving 7,824 participants provided information on 486 human blood metabolites. Outcome information was obtained from a large-scale GWAS meta-analysis of AD, encompassing 21,982 cases and 41,944 controls of Europeans. The primary two-sample MR analysis utilized the inverse variance weighted (IVW) model while supplementary analyses used Weighted median (WM), MR Egger, Simple mode, and Weighted mode, followed by sensitivity analyses such as the heterogeneity test, horizontal pleiotropy test, and leave-one-out analysis. For the further identification of metabolites, replication and meta-analysis with FinnGen data, steiger test, linkage disequilibrium score regression, confounding analysis, and were conducted for further evaluation. Multivariable MR was performed to assess the direct effect of metabolites on AD. Besides, an extra replication analysis with EADB data was conducted for final evaluation of the most promising findings.ResultsAfter rigorous genetic variant selection, IVW, complementary analysis, sensitivity analysis, replication and meta-analysis with the FinnGen data, five metabolites (epiandrosterone sulfate, X-12680, pyruvate, docosapentaenoate, and 1-stearoylglycerophosphocholine) were identified as being genetically associated with AD. MVMR analysis disclosed that genetically predicted these four known metabolites can directly influence AD independently of other metabolites. Only epiandrosterone sulfate and X-12680 remained suggestive significant associations with AD after replication analysis with the EADB data.ConclusionBy integrating genomics with metabonomics, this study furnishes evidence substantiating the genetic association of epiandrosterone sulfate and X-12680 with AD. These findings hold significance for the screening, prevention, and treatment strategies for AD
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